The uncertain trajectories and unwanted restrictions placed on individuals by chronic conditions have negative psychological consequences and individuals often require support to adjust and live the life they want. Self-compassion, a composite of psychological skills including mindfulness and self-kindness, is being increasingly recognised for its ability in helping individuals mitigate the stressors presented by a range of problems, including chronic health conditions like inflammatory bowel disease (IBD). IBD is a chronic condition affecting individuals’ digestive tract and there are two prevalent subtypes, Crohn’s disease and ulcerative colitis. The condition is characterised by inflammation in the colon which creates ulcers causing individuals chronic abdominal pain, diarrhoea and fatigue amongst other symptoms. It has recently been estimated that 1 in 100 people live with IBD and its incidence and prevalence is growing across the world, particularly in Western countries. Individuals with IBD report perceiving stigma from society as a result of the conditions’ symptoms and feel associated shame. Internalised psychological distress, low mood and anxiety, is high in those diagnosed with IBD, and the use of avoidant coping strategies like social withdrawal is common to help create a sense of control over the condition. Self-compassion instead encourages individuals to turn towards and connect with their psychological pain, acknowledge underlying stressors in a balanced way and take a flexible approach to coping. This chapter explores the value of self-compassion to individuals living with IBD, the current evidence base, its potential clinical application and future directions for research.