How to organize oneself for adaptation to climate change and natural hazards? This question indicates that besides technical and financial matters, adaptation is closely related with governance and organization challenges. Effective policy making and realization require an enabling government and societal setting with good governance. Especially multi-sectoral plans that involve many ministries, agencies, and stakeholders give these needs even more importance. Delta areas have been the subject of global experiences, also in the preparation of a plan for protection and development of these areas. Bangladesh applied these experiences to its own situation in order to avoid the pitfalls and apply the beneficial lessons learned. Bangladesh has an interesting background of addressing the challenges and issues associated with its delta through water-related and other institutions. The institutional framework for adaptive management of the Delta Plan has been built on both, international experiences and the own rich background, plans and rules. Government organizations are mostly stable, show sometimes even inertia but are also gradually changing due to modernization and influx of new staff or are influenced by changing political situations. Governmental and governance changes will further evolve while climate change and adaptation are ongoing. In other words, institutional reform happens and can be utilized in the transformative approach of adaptation. The aim is to develop an institutional framework which stimulates and facilitates adaptive realization of the BDP 2100. This chapter provides insight in the institutional backgrounds, in analysis and framework needed for execution of the Delta Plan and realization of the long-term vision. Clarity of role, interdependence of actions, and a coordinated approach are essential requirements of the institutional set up for adaptive realization of the Delta Plan.