Urbanization and industrial development are the major contributors to global environmental pollution, especially heavy metals. Metals are typically a part of soil; some are beneficial to plants, while some are toxic to both humans and plants. Once higher concentrations of metals enter into the environment, they become toxic. Then only plants can be removed by accumulation and detoxification processes. Nowadays, heavy metal contamination is a global problem, particularly in developing nations like India. Heavy metal toxicity reported worldwide has caused harmful effects on life, including plants and animals. Therefore, the chapter focuses on sources of heavy metals and their influences on plant and human health. This chapter also focuses on metal remediation technologies and the metal absorption capabilities of urban tree species. The technique identification of the higher metal accumulation capability of trees will be helpful for metal remediation from urban areas’ environments (air, water, and soil). Because trees can store elements long-term, we can recreate historical changes in heavy metals (HMs) concentrations in ecosystems. Therefore, this chapter will provide information on minimizing HMs from air, soil, and water, as well as human health impacts and environmental sustainability.