Pharmacists play a vital role on the health-care team, regardless of the practice setting. There are a variety of certificate and training opportunities to advance knowledge of disease state management of diabetes and obesity. Pharmacists are well positioned to provide recommendations for medications in diabetes that promote weight loss and/or weight loss medication strategies in people with weight classified as overweight or are living with obesity. Pharmacists have a crucial role in clinical scenarios to conduct thorough interviews, evaluate overall health, make comprehensive, guideline-directed recommendations, provide education and follow-up, and facilitate medication affordability and access.