Many unaccompanied children who seek asylum in the UK have been separated from their families by war. In this chapter, findings from international research are integrated with reflections from social workers from local authorities and independent agencies; carers; policy advisers; academics; and an independent guardianship service manager. The aim is to bridge learning from varied professional perspectives and to identify implications for social work education, practice, and policy. Significant concerns are raised about the impact of insular legislative and systemic reforms upon children’s rights. Exploration of this topic illustrates the need for a global and local perspective in social work and a focus on rights, relationships, and resilience for each child in context.