Photoluminescence-based biosensors, such as Fluorescence Resonance Energy Transfer (FRET) and chemiluminescence assays, have revolutionized biosensing and diagnostics. Their unique mechanisms, coupled with advancements in fluorescent materials and detection technologies, continue to expand their applications, offering unparalleled precision and sensitivity in detecting biological and chemical targets. This chapter provides comprehensive details on photoluminescence for biosensing and diagnostics, biosensors utilizing photoluminescent emitters, and the in vitro and in vivo diagnostic applications for disease biomarker detection and imaging of cellular processes.

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Photoluminescence for Biosensing and Diagnostics

  • Chiamaka Linda Mgbechidinma,
  • Samuel Ukpong Okon,
  • Omoremime Elizabeth Dania,
  • Fatai Oladipupo Oladoyinbo,
  • Chibueze Anslem Mgbechidimma,
  • Olayinka Oderinde,
  • Isaac Sewanu Bankole,
  • Olubunmi Ayoni Ogundiran

摘要

Photoluminescence-based biosensors, such as Fluorescence Resonance Energy Transfer (FRET) and chemiluminescence assays, have revolutionized biosensing and diagnostics. Their unique mechanisms, coupled with advancements in fluorescent materials and detection technologies, continue to expand their applications, offering unparalleled precision and sensitivity in detecting biological and chemical targets. This chapter provides comprehensive details on photoluminescence for biosensing and diagnostics, biosensors utilizing photoluminescent emitters, and the in vitro and in vivo diagnostic applications for disease biomarker detection and imaging of cellular processes.