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Thermal tissue injuries lead to heat denatured necrotic tissue, commonly known as burn eschar. This eschar can induce both local and systemic complications, including inflammation and infectionInfection which also contribute to the breakdown of the escharEschar through autolysis. This process of “conservative” treatment through topical wound medication and dressing changes exacerbates both local and systemic insults as well as the development of granulation tissue, ultimately leading to heavy scarringScarring through healing by secondary intention.

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NexoBrid Enzymatic Debridement and Minimally Invasive Modality for Burn Care

  • 章节

  • 发表日期：

    2025年

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  • Lior Rosenberg,
  • Hajime Matsumura

摘要

Thermal tissue injuries lead to heat denatured necrotic tissue, commonly known as burn eschar. This eschar can induce both local and systemic complications, including inflammation and infectionInfection which also contribute to the breakdown of the escharEschar through autolysis. This process of “conservative” treatment through topical wound medication and dressing changes exacerbates both local and systemic insults as well as the development of granulation tissue, ultimately leading to heavy scarringScarring through healing by secondary intention.