With the rapid development of automobile industry, automobile steering knuckle is one of the most important parts on automobile steering bridge, therefore, the design of its high-efficiency production process has become the inevitable choice for the development of automobile steering knuckle. In view of the characteristics of automobile steering knuckle, such as complex structure, many machining parts, high machining requirements, difficult positioning and clamping, and large production batch, combined with the actual machining process of automobile steering knuckle, including production line layout and position arrangement, production rhythm and production capacity status quo, discussed and analyzed the production line of our car steering knuckle specific process problems. According to the structure characteristics of automobile steering knuckle, the machining technology scheme is worked out, and the machining positioning datum, part clamping scheme and balance analysis are given. Based on the Quest platform, the simulation test of maximizing the machining efficiency and optimizing the man-hour configuration is carried out, and the simulation results are analyzed and evaluated, the validity of the research is proved. Finally, the optimal process plan of the automobile steering knuckle is given, which is helpful to the reference design of the machining process.