Data Mining is a process of extracting valuable information and knowledge that people have not observed from a large number of complicated data. Massive data mining based on cloud computing can optimize the dynamic resource scheduling and allocation of information. The application of data mining technology in computer software engineering can quickly find out the data which is beneficial to software engineering management, thus providing useful information for software development and management. Data mining technology has significant application advantages in software vulnerability detection, fault repair, source code development and other fields. This paper proposes the application of data mining technology to software engineering on the basis of cloud computer. The experimental results show that the data mining technology proposed in this paper can effectively improve the quality of software engineering development and management under the cloud computing platform.