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Optical coherence tomography (OCT) provides real-time, cross-sectional, as well as en face skin images to a depth of up to 2 mm. OCT is a convenient, fast bedside imaging technology that is commercially available from several companies. In dermatology, the pretherapeutic delineation of keratinocyte carcinomas has been a natural focus for applied OCT research, and more recently, OCT research has shifted toward noninvasive monitoring of skin cancer treatments. Previous studies have found good agreement between OCT images and histopathological images. Cryosurgery is a fast and easy treatment modality frequently used for the treatment of actinic keratosis (AK) lesions in everyday dermatology practice. Cryosurgery with liquid nitrogen freezes and destroys the epidermis containing the AK. This chapter outlines the capability of OCT to monitor cryosurgery.

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Optical Coherence Tomography and Cryosurgery

  • 章节

  • 发表日期：

    2025年

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  • Terese von Knorring,
  • Mette Mogensen,
  • Christina A. Banzhaf,
  • Gregor Jemec,
  • Lotte Themstrup

摘要

Optical coherence tomography (OCT) provides real-time, cross-sectional, as well as en face skin images to a depth of up to 2 mm. OCT is a convenient, fast bedside imaging technology that is commercially available from several companies. In dermatology, the pretherapeutic delineation of keratinocyte carcinomas has been a natural focus for applied OCT research, and more recently, OCT research has shifted toward noninvasive monitoring of skin cancer treatments. Previous studies have found good agreement between OCT images and histopathological images. Cryosurgery is a fast and easy treatment modality frequently used for the treatment of actinic keratosis (AK) lesions in everyday dermatology practice. Cryosurgery with liquid nitrogen freezes and destroys the epidermis containing the AK. This chapter outlines the capability of OCT to monitor cryosurgery.