Technological innovations in health care and rehabilitation have the potential to revolutionize lives, offering groundbreaking tools for diagnosis, treatment, and patient care. Yet, these advancements remain out of reach for many, particularly in underserved communities and low- and middle-income countries (LMICs). Accessibility and affordability are two significant barriers preventing equitable use of these technologies. This chapter explores the deep-rooted challenges that hinder access, including geographic disparities, socioeconomic inequities, and systemic obstacles, such as inadequate infrastructure and digital illiteracy. For example, rural areas often lack access to advanced diagnostic tools like MRI scanners, while high costs and restrictive insurance policies make cutting-edge innovations unattainable for low-income populations. Through case studies such as COVID-19 vaccination disparities, the chapter highlights how systemic issues perpetuate healthcare inequities. The pandemic exposed the stark contrast between high-income countries with quick vaccine rollouts and LMICs struggling with affordability and logistical hurdles. To address these challenges, this chapter presents practical strategies to make healthcare technologies more inclusive. Public–private collaborations, open-source platforms, subsidies, and decentralized manufacturing models like 3D printing emerge as promising solutions. The chapter also emphasizes the role of telehealth and mobile health (mHealth) in bringing cost-effective care to remote regions. Real-world examples, including the Aravind Eye Care System in India and portable diagnostic devices in sub-Saharan Africa, illustrate how innovation and commitment can overcome barriers. Looking ahead, emerging trends such as AI-powered cost optimization, blockchain for transparency, and community-based financing models offer hope for more affordable and accessible healthcare technologies. By embracing a collaborative, human-centered approach, we can ensure these advancements benefit everyone, regardless of income or geography. Bridging the gap in healthcare technology access is not just a technical challenge—it is a moral imperative for building a more equitable future.