Artificial intelligence (AI) has altered the healthcare and evaluation landscapes, offering benefits from time efficiency to increased accuracy and productivity. AI-related healthcare improvements range from increased diagnostic accuracy to more face time with patients and insight into patients’ medical needs. It has helped to build patient- and community-based healthcare evaluation capacity; helping individuals and communities become more self-determined concerning their health. Simultaneously, AI is transforming the field of evaluation, increasing evaluator’s efficiency and precision. These synergistic changes are taking place in a rapidly evolving environment, making it imperative that AI healthcare products and services be continually evaluated. In addition, regulatory agencies need to be informed about AI-related developments in the healthcare and evaluation arena to help them appropriately guide and monitor these developments and innovations.