The advancements in wildlife reproductive science present both ethical challenges and opportunities for the conservation and management of wild populations. This chapter delves into the ethical dimensions surrounding the applications of wildlife reproductive research and technologies. We emphasize the need for a comprehensive ethical analysis encompassing various dimensions such as social values, animal welfare, research ethics, conservation strategies, and environmental ethics. Advancements in wildlife reproduction science and technology can influence our health and views of society, the health and lives of wild animals, the conservation and management of populations living in the wild or kept as genetic reserves, and, ultimately, our relationship with the environment and our very ideas of nature and naturalness. We analyze and discuss from an ethical standpoint some key issues, including taxa prioritization, boundary problems, animal welfare, gathering and managing samples, technological dependency, respect for naturalness, and compliance with international regulations.