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Depression and burnout represent distinct psychological conditions that exert significant impacts on an individual’s overall well-being and functional capabilities. Depression is characterized by persistent feelings of sadness, diminished interest in activities, and contemplation of death or suicide, while burnout manifests as a response to prolonged occupational stress, resulting in emotional exhaustion and diminished personal achievement. This exploratory investigation utilized big data from the Lifelines Biobank, encompassing over 9500 participants in the Netherlands. Principal Component Analysis (PCA) and correlation analyses were employed in the study. The findings elucidate the pivotal roles of social support and physical activity in mitigating both burnout and depression. Individuals with heightened social influence and popularity reported lower burnout scores. Additionally, glucose levels emerged as a biomarker influencing the interplay between depression, burnout, and demographic characteristics. Elevated blood sugar levels were linked to an augmented risk of depression and negative emotional states, underscoring the significance of maintaining stable glucose levels. Demographic profiles were identified as influential factors in depression and burnout experiences. Higher income and education levels correlated with reduced burnout scores, while an increased number of dependents, such as family members and children, was associated with enhanced social support and diminished depression. In conclusion, individuals characterized by robust social support, engagement in physical activity, and maintenance of stable glucose levels exhibited lower susceptibility to depression and burnout. Moreover, demographic factors played a significant role in the likelihood of encountering these mental health conditions. This research enhances our comprehension of the intricate intersections between societal and individual factors, offering insights to guide endeavors aimed at mitigating the prevalence of depression and burnout within society.

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Mitigating Mental Health Struggles: The Importance of Social Support, Glucose Control, and Demographic Factors in Depression and Burnout

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  • 发表日期：

    2025年

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  • Vaidehi Sharma,
  • Jolly Masih,
  • Rajkumar Rajasekaran,
  • Dinesh Kumar Yadav,
  • K. Govinda

摘要

Depression and burnout represent distinct psychological conditions that exert significant impacts on an individual’s overall well-being and functional capabilities. Depression is characterized by persistent feelings of sadness, diminished interest in activities, and contemplation of death or suicide, while burnout manifests as a response to prolonged occupational stress, resulting in emotional exhaustion and diminished personal achievement. This exploratory investigation utilized big data from the Lifelines Biobank, encompassing over 9500 participants in the Netherlands. Principal Component Analysis (PCA) and correlation analyses were employed in the study. The findings elucidate the pivotal roles of social support and physical activity in mitigating both burnout and depression. Individuals with heightened social influence and popularity reported lower burnout scores. Additionally, glucose levels emerged as a biomarker influencing the interplay between depression, burnout, and demographic characteristics. Elevated blood sugar levels were linked to an augmented risk of depression and negative emotional states, underscoring the significance of maintaining stable glucose levels. Demographic profiles were identified as influential factors in depression and burnout experiences. Higher income and education levels correlated with reduced burnout scores, while an increased number of dependents, such as family members and children, was associated with enhanced social support and diminished depression. In conclusion, individuals characterized by robust social support, engagement in physical activity, and maintenance of stable glucose levels exhibited lower susceptibility to depression and burnout. Moreover, demographic factors played a significant role in the likelihood of encountering these mental health conditions. This research enhances our comprehension of the intricate intersections between societal and individual factors, offering insights to guide endeavors aimed at mitigating the prevalence of depression and burnout within society.