Climate change significantly affects the physiology of mango trees, influencing their growth, flowering, fruiting, and overall productivity. Rising temperatures, fluctuating rainfall patterns, and increased frequency of extreme weather events disrupt the delicate balance of physiological processes such as photosynthesis, transpiration, and nutrient uptake. Prolonged heat stress can impair pollination and fruit set, while irregular water availability impacts root function and nutrient assimilation. Additionally, shifts in phenology, such as altered flowering and fruiting periods, may result in reduced yield and quality. Understanding the physiological responses of mango trees to these climatic stressors is crucial for developing adaptive management strategies. Approaches such as selecting climate-resilient cultivars, optimizing irrigation practices, and enhancing soil health through organic amendments can mitigate the adverse effects of climate variability. This knowledge provides a foundation for improving mango tree resilience, ensuring sustainable production, and meeting future food security demands amidst a changing climate.