The sector most affected by climate change is agriculture. Greenhouse gases are the most fundamental factors in climate change. Reducing the emissions of these gases also affects agricultural production. The temperature increases due to global warming rise every year. The change in temperature affects the photosynthesis level of plants, which in turn affects the synthesis of antioxidant compounds and the quality of the product after harvest. Increasing ozone levels cause changes in important quality parameters. Different types of visual damage and physiological disorders are seen in plants. Temperatures above optimum temperatures cause irreversible damage to plant growth and development. High temperatures cause plants to develop faster, thus shortening the vegetation period, resulting in lower yields. Temperature affects physiological and biochemical processes in plants. In many plants, growth is slow at temperatures above 40 °C and below 10 °C due to reduced or inhibited photosynthesis. The physiological processes most affected by temperatures above or below optimum growth temperatures for plants are photosynthesis, growth and respiration. Similarly, biochemical changes such as changes in the viscosity, permeability and fluidity of the cell membrane also occur. In addition, there are changes in the synthesis of antioxidant enzymes and activities. In this review study, it was aimed to evaluate the general cytogenetics and phytochemicals of the plant in mango cultivation along with global climate change.