The Great Comet of 1618 had the most profound effect on poetry of any comet in history, most notably in its appearance in John Milton’s epic poem Paradise Lost, 49 years after the comet’s appearance. More than 100 contemporary works were printed on the comet of 1618. This chapter examines many of those containing poetry written especially for them, a serious examination of which has so far been absent from the history of astronomy studies. Sources in English and Dutch are covered thoroughly. The key poem in this study is the one written by King James I of England. Through an imbricated reading strategy, the multiple layers of meaning embedded in these poems are explicated for the first time.