In this chapter the dynamics of changes in the structure and composition of the automobile fleet on the territory of the Krasnoyarsk region is considered. The statistics of road accidents in the Krasnoyarsk region due to driving a vehicle with some failures or under conditions which prohibit the operation of the vehicle is analyzed. The legal acts regulating the changes to the design of vehicles in the Russian Federation, as well as the permitted and prohibited changes to the design of the vehicles are considered. The statistical data related to the introduction of changes to the design of the vehicles on the territory of the Krasnoyarsk region are analyzed, namely: the structure of the vehicle fleet which design was changed and registered in accordance with the procedure provided by the legislation of the Russian Federation. Based on the results of statistics, conclusions about the goals and features of making changes to the vehicle design in Krasnoyarsk region have been draw.