Neurocutaneous syndromes consist of neurologic issues in addition to cutaneous findings. One of the most common disorders that may be identified in the adolescent age group is neurofibromatosis. Adolescents with neurofibromatosis are predisposed to both benign and malignant tumors. Neurofibromatosis is an example of a RASopathy. RASopathies are a group of genetic conditions caused by changes in the genes that control the Ras/mitogen-activated protein kinase (Ras/MAPK) pathway.