Traditionally, digital and palmar fasciectomy treatments for Dupuytren’s disease were commonly performed in the main operating room with the patient under general anesthesia with the use of tourniquet. Due to concerns regarding possible digital necrosis, local anesthesia with epinephrine in the fingers was generally avoided. However, over the course of the past several decades this myth has been debunked and the wide-awake local anesthesia with no tourniquet (WALANT) technique has been implemented for many hand procedures. Although it has been described in diverse hand surgeries, many surgeons are hesitant to perform WALANT in Dupuytren’s contracture due to a concern of a bloody field with local anesthesia, vasospasm from digital ischemia, and/or their lack of experience with this novel technique. In this chapter, we will discuss our method for successful correction of Dupuytren’s contracture using WALANT. Additionally, we will be reviewing safe sterility practices of the procedure and thoroughly examine the advantages, outcomes, cost benefits, patient considerations, and contraindications to this technique.