Modern healthcare infrastructures and services are dependent on advanced data analytics, sensing and communication technologies that include 5G/6G networks, Artificial intelligence (AI), Internet of Medical Things (IoMT), Information Technology (IT), and Operational Technology (OT). This integration incurs a large vulnerability surface and cyber attackers can exploit those vulnerabilities to wage successful attacks against modern healthcare infrastructures and services. Therefore, identifying potential vulnerabilities in healthcare infrastructures and services and securing end-to-end monitoring of sensitive healthcare infrastructures and services are crucial for achieving resilient healthcare infrastructures and services. In this paper, we propose an architecture designed to enhance the resilience of healthcare infrastructures and services. This architecture is centered around the concept of Adaptive Cognitive Digital Twins (ACDTs), which are capable of orchestrating adaptive defenses to proactively respond to anticipated cyber attacks. Our architecture has seven layers. We detail the functions at each layer of the architecture to guide the design and development of mechanisms that can be employed at each layer.