Children are particularly vulnerable in disaster situations due to their distinct physical, developmental, and psychological characteristics, requiring specialized medical attention. This chapter delves into the key aspects of pediatric trauma management during disaster responses, focusing on the unique challenges posed by the care of injured children in resource-limited and chaotic environments. It addresses how a child’s smaller body size, thinner skin, and developing immune system influence the patterns and severity of trauma, as well as how these factors impact clinical decision-making and treatment priorities. The chapter emphasizes the importance of early recognition and management of life-threatening conditions in pediatric patients, such as airway compromise, fluid imbalance, and shock, which can progress rapidly in children compared to adults. Given their smaller blood volume and increased susceptibility to hypothermia and infection, children require tailored interventions to stabilize and treat traumatic injuries. This chapter also discusses the importance of ensuring adequate supplies and equipment designed specifically for pediatric patients in disaster settings, from medical tools to emergency medications. In addition, the chapter highlights the psychological impact of disasters on children, stressing the need for immediate psychological support alongside physical care. Integrating pediatric-specific protocols into disaster preparedness plans is essential, and this chapter provides practical guidelines for triage, emergency treatment, and the organization of pediatric trauma care in the field. Drawing from both clinical experience and evidence-based practices, the chapter aims to equip healthcare providers with the knowledge and strategies necessary to optimize pediatric trauma care during disaster responses, improving outcomes for the most vulnerable population—children.