This chapter reviews the literature on a sample of occupations commonly reported to have an increased suicide risk, based on systematic reviews population-based surveillance, and U.S. government reports. These occupations include: first responders, veterinarians, construction workers, healthcare workers, and the military. This chapter primarily focuses on U.S. studies and highlights some of the risk and protective factors associated with suicide among these five occupations. While there are no legal requirements in the U.S. that require individuals to report suicides or a mandatory reporting requirement, there are, however, two distinct federal data systems that capture suicides—The National Violent Death Reporting System (NVDRS) and the Census of Fatal Occupational Injuries. The NVDRS collects data on all violent deaths as defined as “a death resulting from the intentional use of physical force or power against oneself, another person, or against a group or community.“ The NVDRS data collection began in 2003 with six participating states and has expanded over time. The Centers for Disease Control and Prevention (CDC) now provides NVDRS funding to all 50 states, the District of Columbia, and Puerto Rico. The CFOI is a Federal-State cooperative program implemented in all 50 States and the District of Columbia since 1992 to compile counts of fatal work injuries. CFOI only includes suicides that occur in a workplace.