Since the 1990s, emerging challenges—such as those related to human rights, pandemics, terrorism—which diverge from traditional military and state conflicts, have gradually redefined the interpretation of the maintenance of peace and security at an international level. The UNSC, as the only and main body for preserving international peace, has thus progressively been facing these challenges despite not specifically being addressed beforehand in its mandate. Despite the structural imbalance of power between the permanent members and the elected members (E10), at the disadvantage of the later, this chapter depicts, through documentary research involving primary and secondary sources and two case studies, how small and regional powers who become elected members in the institution strategically establish and use a variety of informal tools and mechanisms for agenda-setting,influencing decision-making. This chapter, through the ongoing work on the topics of climate change and cybersecurity, contributes to further comprehending how non-traditional threats are addressed by the E10 and how their potential increased agency, through Arria meetings and strategies, establishes them as debate conveners. The results of this research indicate that despite the variety of challenges in influencing the decisions outcomes because of the veto power of permanent members, small and regional powers have managed to circumvent disputes and transform them into compromises through the use of Arria meetings for agenda-setting in order to further advance discussion of these topics at the UNSC. It thus addresses an issue which is rarely examined in the current literature.