Dysgeusia is an unpleasant alteration in taste, in which nerve injury, head and neck trauma or surgery, infections, and oncologic treatment may be contributing factors. Changes in taste due to chemotherapy and or head and neck radiotherapy may contribute to the high prevalence of malnutrition in cancer patients. In a recent clinical trial involving oncologic patients, a significant reduction in the severity of dysgeusia was observed when treated with photobiomodulation (PBM). However, the biological mechanisms explaining how PBM may benefit dysgeusia patients are not clear, as it was a reported unexpected clinical finding.