This study presents a deterministic model for tuberculosis transmission in Cameroon’s Adamaoua region, considering both pulmonary and extra-pulmonary cases. Real data from 2015 to 2022 is used to determine the best model, and the model is formulated using integer and fractional-order derivatives. The study demonstrates the existence and uniqueness of solutions, computes the basic reproduction number, \(R_{0}\) , and studies the asymptotic stability of the tuberculosis-free equilibrium point. Through model calibration with real data of the Adamaoua region, we obtain that \(R_{0}=4.1683\) which implies that tuberculosis is endemic in the Adamaoua region. Numerical simulations are performed to validates theoretical results.

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Fractional Dynamics and Prediction of the Spread of Tuberculosis in the Adamaoua Region of Cameroon

  • Hamadjam Abboubakar,
  • Manasse Djouassoum,
  • Sylvain Ardo Gouroudja Banbeto,
  • Joseph Yves Effa

摘要

This study presents a deterministic model for tuberculosis transmission in Cameroon’s Adamaoua region, considering both pulmonary and extra-pulmonary cases. Real data from 2015 to 2022 is used to determine the best model, and the model is formulated using integer and fractional-order derivatives. The study demonstrates the existence and uniqueness of solutions, computes the basic reproduction number, \(R_{0}\) , and studies the asymptotic stability of the tuberculosis-free equilibrium point. Through model calibration with real data of the Adamaoua region, we obtain that \(R_{0}=4.1683\) which implies that tuberculosis is endemic in the Adamaoua region. Numerical simulations are performed to validates theoretical results.