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Upon treatment of primary amides with hypohalites, primary amines with one less carbon are obtained via the intermediacy of isocyanate. Also known as the Hofmann degradation reaction.

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Hofmann Rearrangement

  • 章节

  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Upon treatment of primary amides with hypohalites, primary amines with one less carbon are obtained via the intermediacy of isocyanate. Also known as the Hofmann degradation reaction.