Also known as the Gewald aminothiophene synthesis, the Gewald reaction is the base-promoted aminothiophene formation from ketone, α-active methylene nitrile and elemental sulfur.

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Gewald Reaction

  • Jie Jack Li

摘要

Also known as the Gewald aminothiophene synthesis, the Gewald reaction is the base-promoted aminothiophene formation from ketone, α-active methylene nitrile and elemental sulfur.