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Condensation reaction of thioglycolic acid derivatives with α,β-acetylenic esters, which upon treatment with base result in the formation of 3-hydroxy-2-thiophenecarboxylic acid derivatives.

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Fiesselmann Thiophene Synthesis

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Condensation reaction of thioglycolic acid derivatives with α,β-acetylenic esters, which upon treatment with base result in the formation of 3-hydroxy-2-thiophenecarboxylic acid derivatives.