Oxidation of aryl aldehydes or aryl ketones to phenols using basic hydrogen peroxide conditions. Cf. A variant of the Baeyer–Villiger oxidation where an aliphatic carbonyl is replaced by an aryl carbonyl, allowing for expulsion of a stabilized hydroxyl leaving group under basic conditions.

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Dakin Oxidation

  • Jie Jack Li

摘要

Oxidation of aryl aldehydes or aryl ketones to phenols using basic hydrogen peroxide conditions. Cf. A variant of the Baeyer–Villiger oxidation where an aliphatic carbonyl is replaced by an aryl carbonyl, allowing for expulsion of a stabilized hydroxyl leaving group under basic conditions.