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Transformation of diols to the corresponding olefins by sequential treatment with 1,1′-thiocarbonyldiimidazole (TCDI) and trimethylphosphite. Also known as Corey–Winter reductive elimination, or Corey–Winter reductive olefination.

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Corey–Winter Olefin Synthesis

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Transformation of diols to the corresponding olefins by sequential treatment with 1,1′-thiocarbonyldiimidazole (TCDI) and trimethylphosphite. Also known as Corey–Winter reductive elimination, or Corey–Winter reductive olefination.