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Also known as the Staudinger reaction. [2 + 2]-Cycloaddition of ketene and imine to form β-lactams. Other coupling partners for ketenes include olefins to give cyclobutanone and carbonyls to give cyclobutanone and carbonyl to give β-lactone.

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Staudinger Ketene Cycloaddition

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Also known as the Staudinger reaction. [2 + 2]-Cycloaddition of ketene and imine to form β-lactams. Other coupling partners for ketenes include olefins to give cyclobutanone and carbonyls to give cyclobutanone and carbonyl to give β-lactone.