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The Povarov reaction is the inverse electron-demand aza-Diels–Alder reaction, a [4 + 2] cycloaddition between an N-arylimine (as the diene) and an electron-rich olefin (as the dienophile), which gives tetrahydroquinolines or substituted quinolines as the product.

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Povarov Reaction

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

The Povarov reaction is the inverse electron-demand aza-Diels–Alder reaction, a [4 + 2] cycloaddition between an N-arylimine (as the diene) and an electron-rich olefin (as the dienophile), which gives tetrahydroquinolines or substituted quinolines as the product.