Hyperthermia has been shown to enhance the anti-tumour effects of DNA damaging treatments including radiotherapy and chemotherapy. Although there are randomised controlled trial data to support the use of hyperthermia in combination with radiotherapy in head and neck cancers, this evidence has largely been disregarded by most head and neck oncologists due to these studies being conducted many years ago with older radiotherapy techniques and hyperthermia technologies. Therefore, new larger randomised trials using up-to-date modern radiotherapy machines and new hyperthermia technology are required. However, heating deep-seated head and neck tumours efficiently with accurate temperature monitoring of these areas could pose technical challenges. This article discusses the recent advance in the new deep hyperthermia technology and the potential clinical trials of the combination of deep hyperthermia with standard treatments such as radiotherapy and immunotherapy, which could change practice in the management of head and neck cancers.