This chapter focuses on the development of a standardized Nurse Curriculum in vaccination, addressing the need for harmonized competencies across Europe. Despite the crucial role of nurses in infection prevention, disparities in training and certification limit their professional autonomy. By proposing a postgraduate curriculum tailored to vaccination, this initiative seeks to unify education, foster continuing professional development, and strengthen leadership in public health. Standardizing nursing education will ensure consistent competency, improve care outcomes, and enhance nurses’ ability to combat misinformation. Ultimately, this curriculum empowers nurses to lead in vaccination efforts, reinforcing their essential role in infection prevention