One of the biggest challenges of inland aquaculture is the accumulation of nitrogenous compounds, phosphorus, suspended solids, and organic matter due to nonassimilated fish feeding and sediments in the water of the fish farming ponds, leading to nutrient-rich effluents that can cause eutrophication, ecosystem imbalance, toxicity, and contamination of water sources; what is particularly stressed in artisanal small-scale fish farms in Colombia, where these effluents are usually directly released to the environment. This uncomfortable availability of nutrients and organic loads offers a unique opportunity for circular economy practices by coupling microalgae cultures as a treatment for these contaminated effluents, recovering nutrients, and producing algal biomass as a possible fed of food supplement for fish in juvenile stages, which also allows us to reduce the supply of animal meals as the main component of the fish diet, lower production costs and diversify the income of local fish farmers. In this framework, this contribution presents the CiBELESα project, which applies at the pilot level, a circular bioeconomy concept to lead an improved strategy for sustainable artisanal aquaculture being developed in some localities of the Magdalena River basin in Colombia and some of its first and more featured results.