Soft and loose bedding have long been known to be risk factors for sudden infant death syndrome (SIDS) and sudden unexpected infant death (SUID) and are a particularly high-risk factor in deaths certified as accidental suffocation and strangulation (ASSB). While the use of prone sleeping has decreased with the Safe to Sleep campaign, soft bedding use remains prevalent in the USA. The American Academy of Pediatrics (AAP) recommends that infants sleep on a firm, flat surface with no loose bedding, pillows, or bumpers. In this chapter, we review the basis for each of these recommendations as well as potential barriers to adherence and strategies for helping families consistently place infants in a safe sleep environment.