Essential fatty acids (EFAs) are key strategic ingredients currently being actively considered for the fortification of food by several food and beverage companies to impart known health benefits and value addition, to their food products. Increasing consumer awareness of the health benefits of the essential fatty acids, particularly omega-3s, is generating a wealth of opportunities for their use in functional foods. In recent years, a plethora of omega-3-fortified food products have reached the market, ranging from meat, eggs, and dairy products to cereals, cereal bars, and infant formula. This article reviews various aspects of omega-3 fortification of food products and highlights the compliance of regulatory guidelines applicable to such products.