The Intestinal Epithelial Barrier: The Physical Barrier That Prevents Bacterial Translocation and Gut Inflammation (Genetic and Environmental Factors That Alter IEB)
摘要
The intestinal barrier comprises a single layer of epithelial cells tightly joined to form a physical barrier. Disruption or compromise of the intestinal barrier can lead to loss of control of antigen trafficking and subsequent activation of immune cells, potentially causing an increased risk of chronic inflammation in various tissues and organs.