Startups operate in an environment where time, resources, and funds are extremely scarce, making it essential to maximise efficiency and productivity without necessarily expanding the size of their teams or allocating extensive resources and funds toward activities that can be streamlined. In this high-pressure setting, Generative Artificial Intelligence (Gen AI) offers a suite of tools and techniques designed to optimise operations, reduce costs, and accelerate project timelines. By embracing Generative AI, startups can automate routine tasks, digitise manual processes, retrieve actionable insights from data, and focus their limited human resources on strategic planning and innovation. This not only enhances their competitive edge but also ensures that they can do more with less, paving the way for sustainable growth and scalability. In this chapter, we introduce a three-step AI integration framework detailing how a startup can adopt Gen AI with the aim of optimising and automating processes as well as building new processes, products and business models. We also discuss how Gen AI tools can be actively used in startups by showcasing the author’s experience with various startups.