Complementary and alternative medicine (CAM) is more and more accepted among women to manage their menopausal complaints. Commonly, the terms “alternative” and “complementary” are often used as synonymous by health professionals and public in general, although they refer to different entities. Reasons for use of CAM range from personal beliefs to fear or individual contraindication for hormone therapy. The US National Center for Complementary and Alternative Medicine has defined this class of therapies as a group of diverse medical and health-care systems, practices, and products that are not generally considered to be part of conventional medicine. Most complementary health approaches fall into one of two subgroups; natural products such as herbs, vitamins, minerals, and probiotics that are often sold as dietary supplements or mind and body practices including yoga, chiropractic and osteopathic manipulation, meditation, massage therapy, acupuncture, relaxation techniques, and hypnotherapy, among a huge variety of other therapies. CAM treatments for vasomotor symptoms include a broad range of plant-based therapies such as phytoestrogens, black cohosh, Chinese herbs, and other herbs and cognitive behavioral therapies such as hypnosis, mindfulness training, paced respiration, and acupuncture. Herein we review the characteristics, action mechanism, efficacy, and safety of CAM therapies to manage vasomotor symptoms in menopausal women.