Sustainability and unsustainability are holistic and multifaceted phenomena, defined by environmental, social, and economic factors. Currently, human activities are negatively affecting the Earth at all spatial-temporal scales. Some of the examples are (1) the unbridled use of fossil fuels, (2) deforestation faster than regrowth, (3) the disposal of non-biodegradable waste, like plastic straws and bags, (4) embedded and tele-coupled pollution, and many. Humans are also responsible for the disinformation that exists in society regarding sustainability and unsustainability. Therefore, a unified definition of sustainability and the development of new concepts and indicator-based methodologies are needed to evaluate the level and nature of the dynamics of sustainability and unsustainability.