Sixty years after Vatican II, the Catholic church still grapples with what it means to be relevant amid forceful currents of social and cultural change including secularisation. The theoretical turn toward post-secularity recognises the mutual relevance of the religious and the secular in settled secular societies, and opens new opportunities for the church. Catholicism’s theological understanding of the interaction between faith and reason and its well-established identity as a public church whose social justice teachings and institutional practices demonstrate concern for the common good, make it well-suited to meet post-secular expectations toward the crafting of a more inclusive society. This chapter presents two illustrative case studies assessing the church’s post-secular competence. The first, focusing on Pope Francis’s discourse on economic inequality and climate change, highlights the church’s ability to carve a relevant, post-secular role. The second, focusing on gay rights, points to the limits in the church’s discourse and the tensions in its navigation between religious/doctrinal ideas and secular lived realities even as it stretches towards an inclusive stance. Concluding reflections highlight insights that may be of interest to other religious (and secular actors) based on Catholicism’s post-secular interaction.