This chapter offers a historical account of the progression of neuropsychology’s use in court cases, from its inception to its present-day importance in forensic settings. Readers learn about the changing relationship between neuroscience and the law through an analysis of significant cases and turning points in neuropsychological jurisprudence. In addition, the chapter delves into the various ways that neuropsychological assessments are used in legal settings, emphasizing how they can be used to evaluate cognitive functioning, establish mental capacity, and examine how a neurological condition or brain injury affects conduct. Case studies demonstrate the various ways in which neuropsychological evaluations are used to guide legal judgments, from determining criminal culpability to providing information in a civil action involving traumatic brain injury. One of the most important things to remember is the complex ways in which neuropsychology has influenced the legal system and the possible future effects on legal practice and policy.