Our understanding of how diet affects the Acne vulgaris pathogenesis is still evolving. Recent studies have revealed a significant correlation between dietary fats and Acne vulgaris. To illustrate, high levels of saturated fatty acids in our diet promote metabolic changes that lead to sebum production and inflammatory Acne vulgaris. Also, Numerous worldwide Observations have found a positive significant correlation between dietary saturated/trans fats and acne vulgaris. On the other hand, omega-6 compounds are linked to the production of inflammatory mediators, while omega-3 compounds are thought to have an opposing or natural effect through their ability to ameliorate acne and reduce sebum production and inflammatory mediators. However, Balancing the omega-6 to omega-3 ratio is crucial for preventing acne development and before that maintaining the overall body health.