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This chapter explores the impact of glycemic index (GI)/glycemic load (GL) on acne vulgaris pathogenesis and symptoms severity. High GI/GL diets can lead to hyperinsulinemia, increasing levels of androgens and IGF-1, which promote sebum production and keratinocyte proliferation, thereby exacerbating acne. Clinical studies have demonstrated that low GI/GL diets can reduce acne severity by potentially improving insulin sensitivity and altering sebum composition. These findings suggest that dietary modifications, specifically adopting low GI/GL diets, can effectively manage acne symptoms and improve patient outcomes.

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Unraveling the Impact of Glycemic Index and Glycemic Load on Acne Vulgaris

  • 章节

  • 发表日期：

    2025年

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  • Nereen A. Almosilhy,
  • Ahmed M. Z. Hassan,
  • Khulood O. Zahran,
  • Esraa M. AlEdani

摘要

This chapter explores the impact of glycemic index (GI)/glycemic load (GL) on acne vulgaris pathogenesis and symptoms severity. High GI/GL diets can lead to hyperinsulinemia, increasing levels of androgens and IGF-1, which promote sebum production and keratinocyte proliferation, thereby exacerbating acne. Clinical studies have demonstrated that low GI/GL diets can reduce acne severity by potentially improving insulin sensitivity and altering sebum composition. These findings suggest that dietary modifications, specifically adopting low GI/GL diets, can effectively manage acne symptoms and improve patient outcomes.