Introduced by the International Federation of Gynecology and Obstetrics (FIGO) in 2001, gestational trophoblastic neoplasia (GTN) is a unified clinical disease classification designed primarily for clinical management. It encompasses all aggressive gestational trophoblastic processes that occur following the evacuation of pregnancy, whether molar or non-molar. Histopathologically, GTN includes persistent mole, invasive mole, metastatic mole, and gestational choriocarcinoma. Placental site trophoblastic tumors (PSTT) and epithelioid trophoblastic tumors (ETT) are sometimes considered part of the GTN spectrum, though they are generally not included in the post-molar GTN entities. It is important to note that the prognostic factors for PSTT and ETT differ significantly from those of the post-molar GTN conditions, such as persistent mole, invasive mole, and choriocarcinoma.