Scholarlink

Coexisting ICI colitis and recurrent C diff infection (CDI) is a challenging scenario given the need for immunosuppression in the setting of active infection. We present a case of a patient with low-grade B cell lymphoma on atezolizumab who developed concurrent ICI colitis and recurrent CDI refractory to standard therapies. Fecal Microbiota Transplantation provided rapid improvement in symptoms while allowing immunosuppression to be administered safely. We observed a sustained response as evidenced by repeat colonoscopies.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Recurrent Clostridioides Difficile Infection and Colitis Post Immune Checkpoint Inhibitor Therapy

  • 章节

  • 发表日期：

    2025年

查看全文
  • Elliot Baerman,
  • Kristin Junek,
  • Rey Cerbas Lavilla,
  • Xin Shelley Wang,
  • Yinghong Wang

摘要

Coexisting ICI colitis and recurrent C diff infection (CDI) is a challenging scenario given the need for immunosuppression in the setting of active infection. We present a case of a patient with low-grade B cell lymphoma on atezolizumab who developed concurrent ICI colitis and recurrent CDI refractory to standard therapies. Fecal Microbiota Transplantation provided rapid improvement in symptoms while allowing immunosuppression to be administered safely. We observed a sustained response as evidenced by repeat colonoscopies.