In China, the construction of arch bridge using the cable-stayed cantilever cast-in-situ method started relatively late and has been rapidly developed and promoted in the past decade. At present, there are many arch bridges that have been built or are under construction using this method. The Qingshui River Bridge with a main span of 248 m is one of the arch bridges with a larger span built using this method in China. The bridge has certain guiding significance for the subsequent construction of arch bridges using this method in China. First of all, this paper lists the design characteristics, construction key technology, and construction monitoring technology of Qingshui River Bridge and analyzes the key contents. Secondly, this paper elaborates on the key working conditions such as mass concrete pouring, temperature effect analysis of joint, and erection optimization of the asymmetric beam. The corresponding construction control methods are proposed, arch bridge which can provide a reference for the construction control and monitoring of the same type of bridge arch.