The research aims to investigate the issue of managing the sustainable development of an enterprise. The research subject is sustainable entrepreneurship development in the chemical engineering industry. The authors employ the principles of sustainable development, which are closely related to the principles of quality management and management concerning environmental and social aspects of organizational activities, as laid out in relevant international and national standards. It was established that effective management of the sustainable development of an enterprise is a priority direction for the economic activity of any entity. The main task, crucial for society and individual entities, is to abandon aggressive and excessive consumption of natural and human resources, thus ensuring the well-being of future generations. Sustainable development should be implemented not only at the global and world levels but also at the regional and organizational levels. The conducted study of managing the sustainable development of the enterprise showed that JSC “Ruzkhimmash” lacks a goal-setting system in the field of sustainability. The authors proposed a set of measures recommended for integration into the process of managing the sustainable development of JSC “Ruzkhimmash.”